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r/migrainescience

+ 3.26%

For anyone that is interested in the science behind migraine disease, or any type of headache, and migraine news.

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https://reddit.com favicon**w.**stagram.com40.00%
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Trending Content in r/migrainescience

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It has been over 2 yrs since I have written most of the articles in the "Migraine Resources" pinned post. In the following months, I am planning on editing each article and adding the latest evidence to them. I will share these articles as I edit them. Once complete, the full pinned post will return

r/migrainescience
88720 days ago

This study found that migraine patients with frequent attacks (4+ monthly days) had impaired brain waste clearance function, which correlated with increased sensory sensitivity and may contribute to migraine progression.

r/migrainescience
7474 days ago

This case series found that patients experienced significant worsening of their migraine patterns after COVID-19 infection, including increased frequency, severity, duration, and reduced medication effectiveness.

r/migrainescience
511416 days ago

This study found that "rizatriptan was ineffective at 1 hour for treating vestibular migraine attacks and had limited benefit on symptoms at 24 hours. Findings do not support using rizatriptan for vestibular migraine attacks."

r/migrainescience
5013a month ago

Primary stroke prevention needs to be talked about more frequenly in the migraine community - especially with evidence of the increased risk. The best way to prevent a stroke-related death is to prevent the first stroke, not to figure it out after the first stroke.

r/migrainescience
464a month ago

This study found that migraine patients exhibit microstructural alterations in both white and gray matter. These neural changes, especially axonal demyelination and loss, become more pronounced as migraine progresses from episodic to chronic. This highlights the need for EARLY intervention.

r/migrainescience
46623 days ago

This study found that the hypothalamus plays an important role in migraine pathophysiology through its altered activation prior to migraine attacks, regulating various neurotransmitters, hormones, and homeostatic functions related to stress, sleep, and feeding.

r/migrainescience
405a month ago

Migraine Comorbidities (Updated for 2025)

r/migrainescience
40614 days ago

Migraine Pathophysiology Explained (Updated for 2025)

r/migrainescience
381717 days ago

All migraine patients should discuss possible statin use with their neurologist. There is enough evidence that not only shows the obvious CV benefit, but also a possible negative correlation with migraine severity and frequency. Statins are a promising adjunct preventive option for migraine.

r/migrainescience
38724 days ago

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